Cardiogenic shock

Last reviewed March 21, 2026

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72Active trials 142Specialists 8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.

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Overview

Clinical phenotype terms— hover any for plain English:

Abnormal left ventricular functionHP:0005162Low-output congestive heart failureHP:0009805Cardiac arrestHP:0001695Impaired myocardial contractilityHP:0006670OrthopneaHP:0012764CracklesHP:0030830Elevated jugular venous pressureHP:0030848Low pulse pressureHP:0030851Increased pulmonary capillary wedge pressureHP:0030876OliguriaHP:0100520

Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events

Jul 2026CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock

Brigham and Women's Hospital — PHASE2

TrialNOT YET RECRUITING

May 2026Routine Versus Provisional Distal Perfusion Catheter Placement in Patients Undergoing Mechanical Circulatory Support

Samsung Medical Center — NA

TrialNOT YET RECRUITING

May 2026Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patients: Comparison With VentilO Algorithm

Laval University

TrialNOT YET RECRUITING

Apr 2026Multidisciplinary Collaborative Care System for Acute Myocardial Infarction Complicated With Cardiogenic Shock

Beijing Anzhen Hospital

TrialNOT YET RECRUITING

Apr 2026Hong Kong Cardiogenic Shock Initiative

Prince of Wales Hospital, Shatin, Hong Kong

TrialNOT YET RECRUITING

Apr 2026INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery

Abiomed Inc. — NA

TrialNOT YET RECRUITING

Mar 2026Personalisation of Mean Arterial Pressure in Adult Patients With Cardiogenic Shock

CMC Ambroise Paré — NA

TrialNOT YET RECRUITING

Feb 2026The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique

University of Genova

TrialNOT YET RECRUITING

Jan 2026On Scene ECPR in Ostrava

University Hospital Ostrava — NA

TrialRECRUITING

Jan 2026Intra-aortic Balloon Counterpulsation (IABC) Compliance

Thomas Jefferson University

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Cardiogenic shock.

20 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

20 recruitingView all trials with filters →

Other20 trials

China Extracorporeal Life Support Registry

Actively Recruiting

· Sites: Beijing, Beijing Municipality

CARDSUP - SWISS Circulatory Support Registry

Actively Recruiting

PI: Lukas C Hunziker Munsch, Prof MD (University of Bern) · Sites: Basel; Bern +3 more · Age: 18–99 yrs

Cardiac Rehabilitation in Patients Acutely Managed for Cardiogenic Shock (ENIGMA)

Actively Recruiting

· Sites: Milan · Age: 18–110 yrs

Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock

Enrolling by Invitation

PI: Mir B Basir, DO (Henry Ford Health) · Sites: Loma Linda, California; Los Angeles, California +15 more · Age: 18–99 yrs

Clinical Characteristics and Outcomes Among STEMI Patients With Cardiogenic Shock at Abu Dhabi City

Actively Recruiting

PI: Abdulmajeed BS Alzubaidi, MD (Abu Dhabi Health Services Co. -SEHA) · Sites: Abu Dhabi, Abu Dhabi Emirate; Abu Dhabi, Abu Dhabi Emirate · Age: 18–99 yrs

Platelet Function and Impella Support

Actively Recruiting

PI: Filippo Consolo, PhD (Università Vita-Salute San Raffaele) · Sites: Milan; Milan · Age: 18–75 yrs

Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

Actively Recruiting

· Sites: Boston, Massachusetts · Age: 18–100 yrs

Post-Acute Phase of Cardiogenic Shock

Actively Recruiting

PI: Cardiovascular department (Mackay Memorial Hospital) · Sites: Taipei · Age: 18–99 yrs

Abiomed Impella RT-DAQ - Observational Study

Active

PI: Alexander Kersten, MD (Uniklinik RWTH Aachen, Klinik für Kardiologie, Ang) · Sites: Aachen, North Rhine-Westphalia; Kiel, Schleswig-Holstein +3 more · Age: 18–99 yrs

Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR

Actively Recruiting

· Sites: Detroit, Michigan; Morristown, New Jersey · Age: 18–100 yrs

Correlation of Cardiac Output Determined by Echocardiography and Indirect Calorimetry in Critically Ill Patients in Cardiogenic Shock on Extracorporeal Circulatory Life Support

Actively Recruiting

PI: Christian Ertmer, MD (University Hospital Muenster, Dept. of Anesthesiol) · Sites: Münster · Age: 18–99 yrs

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

Actively Recruiting

PI: Stavros Drakos, M.D. (University of Utah) · Sites: Weston, Florida; Falls Church, Virginia +1 more · Age: 18–99 yrs

Intra-aortic Balloon Counterpulsation (IABC) Compliance

Actively Recruiting

PI: Matthew S Delfiner, DO, MS (Thomas Jefferson University) · Sites: Philadelphia, Pennsylvania · Age: 18–99 yrs

Early Left Ventricular unLoading by Impella vs Intra-aortic Balloon Pump

Actively Recruiting

PI: Aurore UGHETTO, MD (Montpellier University Hospital, France) · Sites: Montpellier · Age: 18–99 yrs

The Clinical and Hemodynamic Course of Cardiogenic Shocks Hospitalized in Critical Care

Actively Recruiting

· Sites: Amiens · Age: 18–99 yrs

Post-Surgery Extracorporeal Life Support

Actively Recruiting

· Sites: Florence · Age: 18–80 yrs

Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Actively Recruiting

· Sites: Jonesboro, Arkansas; Orange, California +8 more · Age: 18–99 yrs

Pilot Italian Cardiogenic Shock Initiative

Actively Recruiting

PI: Alaide Chieffo, Prof (IRCCS San Raffaele Hospital) · Sites: Chivasso; Cirié +14 more · Age: 18–75 yrs

The ECMOCYP (cytochromes P450 Activity) Study

Actively Recruiting

· Sites: Geneva · Age: 18–99 yrs

SafeTy and Outcome of contemPorary Treatment Strategies for Cardiogenic SHOCK

Actively Recruiting

PI: Dirk Westermann, MD (UHZ) · Sites: Hamburg · Age: 18–99 yrs

Specialists

Showing 25 of 142View all specialists →

SM

Stefan Brunner, MD

HUNTINGTON, NY

Specialist

PI on 1 active trial

Active trials Directions Travel grants

LM

Luciano G Potena, MD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

CS

Carsten Skurk

Specialist

2 Cardiogenic shock publications

Directions Travel grants

CJ

Christian Jung

WORCESTER, MA

Specialist

3 Cardiogenic shock publications

Directions Travel grants

SP

Susanna Price

Specialist

2 Cardiogenic shock publications

Directions Travel grants

JP

Janine Pöss

Specialist

3 Cardiogenic shock publications

Directions Travel grants

MA

Marianna Adamo

Specialist

2 Cardiogenic shock publications

Directions Travel grants

HT

Holger Thiele

Specialist

8 Cardiogenic shock publications

Directions Travel grants

JJ

Jacob C Jentzer

ROCHESTER, MN

Specialist

3 Cardiogenic shock publications

Directions Travel grants

CH

Christian Hassager

Specialist

4 Cardiogenic shock publications

Directions Travel grants

UZ

Uwe Zeymer

Specialist

3 Cardiogenic shock publications

Directions Travel grants

KK

Konstantin A Krychtiuk

Specialist

2 Cardiogenic shock publications

Directions Travel grants

PC

Peter Clemmensen

Specialist

2 Cardiogenic shock publications

Directions Travel grants

AL

Axel Linke

Specialist

2 Cardiogenic shock publications

Directions Travel grants

DM

David A Morrow

Specialist

5 Cardiogenic shock publications

Directions Travel grants

VM

Vanessa Blumer, MD

FALLS CHURCH, VA

Specialist

PI on 1 active trial

Active trials Directions Travel grants

UP

Uwe Zeymer, Prof

Specialist

PI on 1 active trial

Active trials Directions Travel grants

DM

Dirk Westermann, MD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

AM

Antoine Kimmoun, MD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

VM

Valluvan Jeevanandam, MD

CHICAGO, IL

Specialist

PI on 1 active trial

Active trials Directions Travel grants

SM

Shashank Sinha, MD MSc

FALLS CHURCH, VA

Specialist

PI on 1 active trial

Active trials Directions Travel grants

AM

Alexander Kersten, MD

Specialist

Severe acute respiratory syndrome

PI on 2 active trials

Active trials Directions Travel grants

HP

Helle Søholm, MD, PhD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

MP

Martin Frydland, MD, PhD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

EM

Evgeniy Merkulov, MD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

Treatment Centers

8 centers

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Cardiogenic shock.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Cardiogenic shock

Disease timeline:

New recruiting trial: An Interventional Left Ventricular Assist System for Cardiogenic Shock

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: Incidence and Morbidity of Cardiac Rhythm Disorders in Patients Assisted by ECMO-VA for Refractory Cardiogenic Shock

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: Pharmacological and Mechanical Support Approaches in the Management of Acute Heart Failure in the Regional Network Model for the Management of Cardiogenic Shock

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: The ECMOCYP (cytochromes P450 Activity) Study

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: A Study on the Effects of Left Ventricular Unloading in the Setting of VA ECMO Support

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: REMAP ECMO - Beta Receptor Modulation Trial

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: The Role of Swan-Ganz Catheter in Hemodynamic Resuscitation for Patients With Cardiogenic Shock

A new clinical trial is recruiting patients for Cardiogenic shock

New recruiting trial: The Current Status and Clinical OUTcomes of Cardiogenic Shock Patients And the Role of Specialist in Cardiovascular Critical Care Unit

A new clinical trial is recruiting patients for Cardiogenic shock

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Cardiogenic shock

Are there clinical trials for Cardiogenic shock?

Yes — 20 recruiting clinical trials are currently listed for Cardiogenic shock on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Cardiogenic shock?

25 specialists and care centers treating Cardiogenic shock are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.