Overview
Benign idiopathic neonatal seizures (BINS), also known as 'fifth-day fits,' are a type of seizure that occurs in otherwise healthy newborns, typically in the first week of life. The word 'benign' means that these seizures are not caused by a serious underlying brain problem and usually go away on their own without causing lasting harm. 'Idiopathic' means that no clear cause, such as infection, low blood sugar, or brain injury, can be found to explain why the seizures happen. The seizures usually begin between the fourth and sixth day after birth, which is why they are sometimes called 'fifth-day fits.' They can look alarming — a baby may have jerking movements, stiffening of the body, or brief pauses in breathing — but they typically last only a short time. Most babies have multiple seizures over one to three days, and then the seizures stop on their own. The good news is that most babies with this condition go on to develop completely normally. Doctors will run tests to rule out other causes of seizures before making this diagnosis. Treatment is usually short-term, and many babies do not need long-term anti-seizure medication. The outlook for children with this condition is generally excellent.
Also known as:
Key symptoms:
Jerking or twitching movements of the arms, legs, or faceStiffening of the bodyBrief pauses in breathing (apnea)Eye deviation or flickering eye movementsLip smacking or sucking movementsSudden limpnessRepeated seizures over one to three daysSeizures beginning between day four and day six of lifeNormal behavior and alertness between seizures
Sporadic
Usually appears on its own, not inherited from a parent
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for Benign idiopathic neonatal seizures.
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Specialists
View all specialists →No specialists are currently listed for Benign idiopathic neonatal seizures.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Benign idiopathic neonatal seizures.
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Questions for your doctor
Bring these to your next appointment
- Q1.Are you confident that all other causes of seizures have been ruled out in my baby?,Does my baby need to continue anti-seizure medication after going home, and for how long?,What are the chances that my baby will have seizures again later in childhood?,Will this affect my baby's development, learning, or behavior as they grow up?,What signs should I watch for at home that would mean I need to call for emergency help?,How often should my baby be seen for follow-up, and by which specialist?,Is there any genetic testing I should consider, especially if we plan to have more children?
Common questions about Benign idiopathic neonatal seizures
What is Benign idiopathic neonatal seizures?
Benign idiopathic neonatal seizures (BINS), also known as 'fifth-day fits,' are a type of seizure that occurs in otherwise healthy newborns, typically in the first week of life. The word 'benign' means that these seizures are not caused by a serious underlying brain problem and usually go away on their own without causing lasting harm. 'Idiopathic' means that no clear cause, such as infection, low blood sugar, or brain injury, can be found to explain why the seizures happen. The seizures usually begin between the fourth and sixth day after birth, which is why they are sometimes called 'fifth-
How is Benign idiopathic neonatal seizures inherited?
Benign idiopathic neonatal seizures follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Benign idiopathic neonatal seizures typically begin?
Typical onset of Benign idiopathic neonatal seizures is neonatal. Age of onset can vary across affected individuals.