Overview
Annular atrophic lichen planus is a rare clinical variant of lichen planus, a chronic inflammatory disorder that primarily affects the skin. In this variant, lesions characteristically present as ring-shaped (annular) plaques or patches with central atrophy, meaning the skin in the center of the ring becomes thin, depressed, or scarred. The lesions may appear violaceous (purple-hued) at the active border, consistent with typical lichen planus morphology, while the center shows atrophic changes. This subtype predominantly affects the skin, though other forms of lichen planus can involve the mucous membranes, nails, and scalp. Annular atrophic lichen planus is classified under the broader category of lichen planus variants (ICD-10: L43.8 — Other lichen planus). It is considered an uncommon presentation and may be confused with other annular dermatoses such as granuloma annulare, morphea, or annular elastolytic giant cell granuloma. Diagnosis is typically confirmed through clinical examination and skin biopsy, which reveals the characteristic band-like lymphocytic infiltrate at the dermoepidermal junction with damage to basal keratinocytes seen in lichen planus. Treatment follows the general approach used for lichen planus and may include topical corticosteroids, topical calcineurin inhibitors, phototherapy, or systemic immunomodulatory agents in refractory cases. The condition may resolve spontaneously over months to years, though atrophic changes in the skin may persist. There is no specific targeted therapy for this variant, and management is largely symptomatic, aimed at reducing inflammation and preventing progression of skin atrophy.
Also known as:
Adult
Begins in adulthood (age 18 or older)
Treatments
No FDA-approved treatments are currently listed for Annular atrophic lichen planus.
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Specialists
View all specialists →No specialists are currently listed for Annular atrophic lichen planus.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Annular atrophic lichen planus.
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Common questions about Annular atrophic lichen planus
What is Annular atrophic lichen planus?
Annular atrophic lichen planus is a rare clinical variant of lichen planus, a chronic inflammatory disorder that primarily affects the skin. In this variant, lesions characteristically present as ring-shaped (annular) plaques or patches with central atrophy, meaning the skin in the center of the ring becomes thin, depressed, or scarred. The lesions may appear violaceous (purple-hued) at the active border, consistent with typical lichen planus morphology, while the center shows atrophic changes. This subtype predominantly affects the skin, though other forms of lichen planus can involve the muc
At what age does Annular atrophic lichen planus typically begin?
Typical onset of Annular atrophic lichen planus is adult. Age of onset can vary across affected individuals.