Adenovirus infection in immunocompromised patients

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3FDA treatments3Active trials5Specialists8Treatment centers2Financial resources

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Jan 2023Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients

M.D. Anderson Cancer Center — PHASE1

TrialRECRUITING
Aug 2020Viral Specific T-Lymphocytes to Treat Adenovirus or CMV

Jessie L. Alexander — PHASE1, PHASE2

TrialACTIVE NOT RECRUITING
Aug 2019

Harvoni: FDA approved

HARVONI is indicated for the treatment of adults and pediatric patients 3 years of age and older with chronic hepatitis C virus (HCV) genotype 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis, genotype 1 infection with decompensated cirrhosis, for use in combination with ribavirin, and genotype 1 or 4 infection who are liver transplant recipients without cirrhosis or with compensated cirrhosis, for use in combination with ribavirin

FDAcompleted
Mar 2018Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease

M.D. Anderson Cancer Center — PHASE1

TrialRECRUITING
Sep 2017

Descovy: FDA approved

DESCOVY, indicated in combination with other antiretroviral agents, for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 35 kg and also indicated, in combination with other antiretroviral agents other than protease inhibitors that require a CYP3A inhibitor, for the treatment of HIV-1 infection in pediatric patients weighing at least 25 kg and less than 35 kg.

FDAcompleted
Sep 2015Third Party Viral Specific T-cells (VSTs)

Children's Hospital Medical Center, Cincinnati — PHASE2

TrialRECRUITING
Oct 2012

Cystaran: FDA approved

Treatment of corneal cystine crystal accumulation in patients with cystinosis

FDAcompleted
Mar 2011Viral Infections in Healthy and Immunocompromised Hosts

National Institute of Allergy and Infectious Diseases (NIAID)

TrialRECRUITING
Dec 1993

Neutrexin: FDA approved

Concurrent leucovorin administration as an alternative therapy for the treatment of moderate to severe PCP in immunocompromised patients who are intolerant of, or are refractory to, trimethoprim sulfamethoxazole.

FDAcompleted
Jun 1989

Cytovene: FDA approved

Treatment of cytomegalovirus retinitis in immunocompromised patients with AIDS.

FDAcompleted

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

3 available

Descovy

emtricitabine and tenofovir alafenamide· Gilead Sciences, Inc.■ Boxed WarningOrphan Drug
DESCOVY, indicated in combination with other antiretroviral agents, for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 35 kg and also indicated, in combination wit

DESCOVY, indicated in combination with other antiretroviral agents, for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 35 kg and also indicated, in combination with other antiretroviral agents other than protease inhibitors that require a CYP3A inhibitor, for the treatment of HIV-1 infection in pediatric patients weighing at least 25 kg and less than 35 kg.

Cystaran

Cysteamine hydrochloride· Leadiant Biosciences, Inc.Orphan Drug

Treatment of corneal cystine crystal accumulation in patients with cystinosis

Neutrexin

Trimetrexate glucuronate· Medimmune Oncology, Inc.Orphan Drug
Concurrent leucovorin administration as an alternative therapy for the treatment of moderate to severe PCP in immunocompromised patients who are intolerant of, or are refractory to, trimethoprim sulfa

Concurrent leucovorin administration as an alternative therapy for the treatment of moderate to severe PCP in immunocompromised patients who are intolerant of, or are refractory to, trimethoprim sulfamethoxazole.

Clinical Trials

3 recruitingView all trials with filters →
Phase 12 trials
Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients
Phase 1
Actively Recruiting
PI: May Daher, MD (M.D. Anderson Cancer Center) · Sites: Houston, Texas · Age: 1899 yrs
Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease
Phase 1
Actively Recruiting
PI: David Marin (M.D. Anderson Cancer Center) · Sites: Houston, Texas

Specialists

5 foundView all specialists →
MM
May Daher, MD
HOUSTON, TX
Specialist
PI on 1 active trial
DM
David Marin
POMONA, CA
Specialist
PI on 1 active trial
MM
Michael Grimley, MD, MD
CINCINNATI, OH
Specialist
PI on 1 active trial
JM
Jeffrey I Cohen, M.D.
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Financial Resources

2 resources
Descovy(emtricitabine and tenofovir alafenamide)Gilead Sciences, Inc.

Cytovene

Syntex (USA), Inc.

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Travel Grants

No travel grants are currently matched to Adenovirus infection in immunocompromised patients.

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Community

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Latest news about Adenovirus infection in immunocompromised patients

Disease timeline:

New recruiting trial: Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease

A new clinical trial is recruiting patients for Adenovirus infection in immunocompromised patients

New recruiting trial: Third Party Viral Specific T-cells (VSTs)

A new clinical trial is recruiting patients for Adenovirus infection in immunocompromised patients

New recruiting trial: Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients

A new clinical trial is recruiting patients for Adenovirus infection in immunocompromised patients

New recruiting trial: Viral Infections in Healthy and Immunocompromised Hosts

A new clinical trial is recruiting patients for Adenovirus infection in immunocompromised patients

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Adenovirus infection in immunocompromised patients

Are there clinical trials for Adenovirus infection in immunocompromised patients?

Yes — 3 recruiting clinical trials are currently listed for Adenovirus infection in immunocompromised patients on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Adenovirus infection in immunocompromised patients?

5 specialists and care centers treating Adenovirus infection in immunocompromised patients are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Adenovirus infection in immunocompromised patients?

3 patient support programs are currently tracked on UniteRare for Adenovirus infection in immunocompromised patients. See the treatments and support programs sections for copay assistance, eligibility, and contact details.