Actinic lichen planus

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16Specialists8Treatment centers

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Overview

Actinic lichen planus, also known as lichen planus actinicus, lichen planus subtropicus, or summertime actinic lichenoid eruption, is a rare variant of lichen planus that occurs predominantly in sun-exposed areas of the skin. It is considered a photodistributed form of lichen planus and is most commonly reported in individuals living in tropical and subtropical regions, particularly in the Middle East, Africa, and the Indian subcontinent. The condition predominantly affects the skin, with lesions typically appearing on sun-exposed sites such as the face, dorsal hands, forearms, and the V-area of the neck. Clinically, actinic lichen planus presents as annular, nummular (coin-shaped), or plaque-like hyperpigmented to violaceous lesions, often with a characteristic rim of hyperpigmentation. Unlike classic lichen planus, the lesions may appear as dyschromic (dark brown to bluish) patches rather than the typical polygonal, pruritic, purple papules. Some patients experience mild itching, though the condition can also be asymptomatic. The lesions tend to worsen with sun exposure and may improve during winter months or with sun avoidance. Treatment of actinic lichen planus centers on strict sun protection, including the use of broad-spectrum sunscreens and protective clothing. Topical corticosteroids are commonly used as first-line therapy to reduce inflammation. Topical calcineurin inhibitors (such as tacrolimus), antimalarials (hydroxychloroquine), and topical retinoids have also been used with variable success. In more resistant cases, systemic treatments including oral corticosteroids or hydroxychloroquine may be considered. The condition may resolve spontaneously but can leave persistent post-inflammatory hyperpigmentation, which can be cosmetically distressing, particularly in individuals with darker skin tones.

Also known as:

Inheritance

Multifactorial

Caused by a mix of several genes and environmental factors

Age of Onset

Adult

Begins in adulthood (age 18 or older)

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Actinic lichen planus.

View clinical trials →

No actively recruiting trials found for Actinic lichen planus at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Actinic lichen planus community →

Specialists

16 foundView all specialists →
JL
Jovan Lalošević
Specialist
1 Actinic lichen planus publication
RA
Raihan Ashraf
Specialist
1 Actinic lichen planus publication
DA
Divya Aggarwal
Specialist
1 Actinic lichen planus publication
RB
Rajsmita Bhattacharjee
Specialist
1 Actinic lichen planus publication
BR
Bishan D Radotra
Specialist
1 Actinic lichen planus publication
DD
Dipankar De
Specialist
1 Actinic lichen planus publication
MO
Muazzez Cigdem Oba
Specialist
1 Actinic lichen planus publication
MY
Meryem Yuvruk
Specialist
1 Actinic lichen planus publication
RS
Riddhima Singh
Specialist
1 Actinic lichen planus publication
SJ
Sugat Jawade
Specialist
1 Actinic lichen planus publication
BM
Bhushan Madke
Specialist
1 Actinic lichen planus publication
AK
Awatef Kelati
Specialist
1 Actinic lichen planus publication
AR
Asmae Rasso
Specialist
1 Actinic lichen planus publication
SC
Soumia Chiheb
Specialist
1 Actinic lichen planus publication
K&
Katarina Đorđević
Specialist
1 Actinic lichen planus publication
VP
Vera Panzarella
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Actinic lichen planus.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Actinic lichen planus

Disease timeline:

New recruiting trial: SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

A new clinical trial is recruiting patients for Actinic lichen planus

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

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Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Actinic lichen planus

What is Actinic lichen planus?

Actinic lichen planus, also known as lichen planus actinicus, lichen planus subtropicus, or summertime actinic lichenoid eruption, is a rare variant of lichen planus that occurs predominantly in sun-exposed areas of the skin. It is considered a photodistributed form of lichen planus and is most commonly reported in individuals living in tropical and subtropical regions, particularly in the Middle East, Africa, and the Indian subcontinent. The condition predominantly affects the skin, with lesions typically appearing on sun-exposed sites such as the face, dorsal hands, forearms, and the V-area

How is Actinic lichen planus inherited?

Actinic lichen planus follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

At what age does Actinic lichen planus typically begin?

Typical onset of Actinic lichen planus is adult. Age of onset can vary across affected individuals.

Which specialists treat Actinic lichen planus?

16 specialists and care centers treating Actinic lichen planus are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.