Overview
Actinic lichen planus, also known as lichen planus actinicus, lichen planus subtropicus, or summertime actinic lichenoid eruption, is a rare variant of lichen planus that occurs predominantly in sun-exposed areas of the skin. It is considered a photodistributed form of lichen planus and is most commonly reported in individuals living in tropical and subtropical regions, particularly in the Middle East, Africa, and the Indian subcontinent. The condition predominantly affects the skin, with lesions typically appearing on sun-exposed sites such as the face, dorsal hands, forearms, and the V-area of the neck. Clinically, actinic lichen planus presents as annular, nummular (coin-shaped), or plaque-like hyperpigmented to violaceous lesions, often with a characteristic rim of hyperpigmentation. Unlike classic lichen planus, the lesions may appear as dyschromic (dark brown to bluish) patches rather than the typical polygonal, pruritic, purple papules. Some patients experience mild itching, though the condition can also be asymptomatic. The lesions tend to worsen with sun exposure and may improve during winter months or with sun avoidance. Treatment of actinic lichen planus centers on strict sun protection, including the use of broad-spectrum sunscreens and protective clothing. Topical corticosteroids are commonly used as first-line therapy to reduce inflammation. Topical calcineurin inhibitors (such as tacrolimus), antimalarials (hydroxychloroquine), and topical retinoids have also been used with variable success. In more resistant cases, systemic treatments including oral corticosteroids or hydroxychloroquine may be considered. The condition may resolve spontaneously but can leave persistent post-inflammatory hyperpigmentation, which can be cosmetically distressing, particularly in individuals with darker skin tones.
Also known as:
Multifactorial
Caused by a mix of several genes and environmental factors
Adult
Begins in adulthood (age 18 or older)
Treatments
No FDA-approved treatments are currently listed for Actinic lichen planus.
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Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Actinic lichen planus.
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Start the conversation →Latest news about Actinic lichen planus
Disease timeline:
New recruiting trial: SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography
A new clinical trial is recruiting patients for Actinic lichen planus
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Learn how rare disease patients may qualify for SSDI/SSI benefits.
Common questions about Actinic lichen planus
What is Actinic lichen planus?
Actinic lichen planus, also known as lichen planus actinicus, lichen planus subtropicus, or summertime actinic lichenoid eruption, is a rare variant of lichen planus that occurs predominantly in sun-exposed areas of the skin. It is considered a photodistributed form of lichen planus and is most commonly reported in individuals living in tropical and subtropical regions, particularly in the Middle East, Africa, and the Indian subcontinent. The condition predominantly affects the skin, with lesions typically appearing on sun-exposed sites such as the face, dorsal hands, forearms, and the V-area
How is Actinic lichen planus inherited?
Actinic lichen planus follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Actinic lichen planus typically begin?
Typical onset of Actinic lichen planus is adult. Age of onset can vary across affected individuals.
Which specialists treat Actinic lichen planus?
16 specialists and care centers treating Actinic lichen planus are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.