Tuberous sclerosis complex

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At a Glance

Live from database

Regulatory Watchboard

9 events
Jul 2025TANDem-2: Closing the Gap to Interventions for TAND

Vrije Universiteit Brussel — NA

TrialENROLLING BY INVITATION
Jun 2024Treatment With Full-spectrum Cannabis Extract of Refractory Epilepsy Associated With Tuberous Sclerosis Complex (TSC)

Oils4Cure — PHASE3

TrialRECRUITING
Jul 2023Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)

David M. Ritter — NA

TrialRECRUITING
Oct 2021Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

Darcy Krueger — PHASE2

TrialRECRUITING
Jul 2021Observational, Retrospective, Multicenter, Nonprofit Study on the Prevalence of Renal Involvement in Pediatric Patients With Tuberous Sclerosis

IRCCS Azienda Ospedaliero-Universitaria di Bologna — NA

TrialRECRUITING
May 2021Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants

Katarzyna Kotulska — PHASE2, PHASE3

TrialRECRUITING
Dec 2019The Effectiveness and Safety of Resective Epilepsy Surgery for TRE

Beijing Children's Hospital — NA

TrialACTIVE NOT RECRUITING
Jun 2017Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

Novartis Pharmaceuticals — PHASE3

TrialACTIVE NOT RECRUITING
Dec 1995Study of the Disease Process of Lymphangioleiomyomatosis

National Heart, Lung, and Blood Institute (NHLBI) — NA

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

FINANCIAL LANDSCAPE SUMMARY

0

Total programs

No financial assistance programs currently listed for Tuberous sclerosis complex.
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Approved Treatments

2 FDA-approved

Everolimus

(EVEROLIMUS)Orphan drugstandard

Breckenridge Pharmaceutical, Inc.

Kinase Inhibitor [EPC]

12.1 Mechanism of Action Everolimus is an inhibitor of mammalian target of rapamycin (mTOR), a serine-threonine kinase, downstream of the PI3K/AKT pat...

FDA label ↗

Epidiolex

(CANNABIDIOL)Orphan drugstandard

Jazz Pharmaceuticals, Inc.

12.1 Mechanism of Action The precise mechanisms by which EPIDIOLEX exerts its anticonvulsant effect in humans are unknown. Cannabidiol does not appear...

FDA label ↗

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Clinical Trial Landscape

9 active trials
2Phase 3
1Phase 2
5N/A
1PHASE2, PHASE3
9Total recruiting
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Recent News & Research

No recent news articles indexed yet for Tuberous sclerosis complex.
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Specialist Network

Top 6 by expertise

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