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treatment of generalized myasthenia gravis (gMG) in adult and pediatric patients 12 years of age and older who are anti-acetylcholine receptor (AChR) or anti-muscle-specific tyrosine kinase (MuSK) antibody positive
Treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive
treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) or anti-muscle-specific tyrosine kinase (MuSK) antibody positive
treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive
treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive
SOLIRIS: FDA approved
for the treatment of adult patients with generalized Myasthenia Gravis (gMG) who are anti-acetylcholine receptor (AchR) antibody positive
Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
FINANCIAL LANDSCAPE SUMMARY
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Patient Assistance Programs5
Imaavy
(NIPOCALIMAB)Orphan drugJanssen Biotech, Inc.
12.1 Mechanism of Action Nipocalimab-aahu is a human IgG1 monoclonal antibody that binds to neonatal Fc receptor (FcRn), resulting in the reduction of...
Zilbrysq
(ZILUCOPLAN)Orphan drugUCB, Inc.
Complement Inhibitor [EPC]
12.1 Mechanism of Action Zilucoplan binds to the complement protein C5 and inhibits its cleavage to C5a and C5b, preventing the generation of the term...
Rystiggo
(ROZANOLIXIZUMAB)Orphan drugUCB, Inc.
Neonatal Fc Receptor Blocker [EPC]
12.1 Mechanism of Action Rozanolixizumab-noli is a humanized IgG4 monoclonal antibody that binds to the neonatal Fc receptor (FcRn), resulting in the ...
Vyvgart Hytrulo
(EFGARTIGIMOD ALFA AND HYALURONIDASE (HUMAN RECOMBINANT))Orphan drugargenx US
Neonatal Fc Receptor Blocker [EPC]
12.1 Mechanism of Action VYVGART HYTRULO is a coformulation of efgartigimod alfa and hyaluronidase. Efgartigimod alfa is a human IgG1 antibody fragmen...
Vyvgart
(EFGARTIGIMOD ALFA)Orphan drugargenx US
Neonatal Fc Receptor Blocker [EPC]
12.1 Mechanism of Action Efgartigimod alfa-fcab is a human IgG1 antibody fragment that binds to the neonatal Fc receptor (FcRn), resulting in the redu...
SOLIRIS
(ECULIZUMAB)Orphan drugAlexion Pharmaceuticals Inc.
BKEMV
(ECULIZUMAB-AEEB)Orphan drugstandardAmgen Inc
Uplizna
(INEBILIZUMAB)Orphan drugstandardHorizon Therapeutics USA, Inc.
CD19-directed Cytolytic Antibody [EPC]
12.1 Mechanism of Action The mechanism by which inebilizumab-cdon exerts its therapeutic effects in NMOSD, IgG4-RD, and gMG is presumed to involve bin...
Orhideja Stomnaroska
1PJU University Clinic for Gynecology and Obstetrics
Renata Dimitrioska
1PJU University Clinic for Gynecology and Obstetrics
Jenny Linnea Victoria Lindroos
linical Medicine
Marte-Helene Bjørk
linical Medicine
Nils Erik Gilhus
linical Medicine
Sanja Ristovska
1PJU University Clinic for Gynecology and Obstetrics