Squamous cell carcinoma of head and neck

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At a Glance

Live from database

Regulatory Watchboard

10 events
Sep 2026Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions

University of Massachusetts, Boston — PHASE2

TrialNOT YET RECRUITING
May 20265-Fluorouracil Response and Optimization STudy (The FROST Trial)

Washington University School of Medicine — PHASE2

TrialNOT YET RECRUITING
May 2026A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)

University of Maryland, Baltimore — PHASE2

TrialNOT YET RECRUITING
Apr 2026Study Evaluating [18F]NOTA-ABY030 for Safety and Tolerability of Indeterminate Primary and/or Metastatic Disease in Head and Neck Squamous Cell Carcinoma

Vanderbilt-Ingram Cancer Center — PHASE1

TrialNOT YET RECRUITING
Apr 2026Lattice-Based Radiotherapy and Chemo-Immunotherapy for Oral Cavity Squamous Cell Carcinoma

NYU Langone Health — PHASE1

TrialNOT YET RECRUITING
Mar 2026Nano-Carbon Iron Suspension Injection Combined With Radiotherapy for Solid Tumors Phase II Clinical Trial

Sichuan Enray Pharmaceutical Sciences Company — PHASE2

TrialNOT YET RECRUITING
Mar 2026Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas

Fox Chase Cancer Center — PHASE1

TrialNOT YET RECRUITING
Feb 2026ABY-029 Head & Neck Trial

Dartmouth-Hitchcock Medical Center — PHASE1

TrialNOT YET RECRUITING
Feb 2026Trial of a Personalized and Adaptive Neoantigen Dose-Adjusted Vaccine Concurrently With Pembrolizumab

UNC Lineberger Comprehensive Cancer Center — PHASE1

TrialNOT YET RECRUITING
Feb 2026A Comprehensive Multiomic Biomarker Evaluation Across Two Single-arm Cohorts to Elucidate Mechanisms of Response and Resistance in Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC)

University Health Network, Toronto — PHASE2

TrialNOT YET RECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

2 programs

FINANCIAL LANDSCAPE SUMMARY

2

Total programs

2

Open now

Patient Assistance Programs2

OPDIVO

E.R. Squibb & Sons, L.L.C.

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Blenoxane

Bristol-Myers Squibb Pharmaceutical Research Institute

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Approved Treatments

3 FDA-approved

Blenoxane

(Bleomycin sulfate)Orphan drugstandard

Bristol-Myers Squibb Pharmaceutical Research Institute

Mechanism of Action Although the exact mechanism of action of bleomycin is unknown, available evidence indicates that the main mode of action is the i...

FDA label ↗

Erbitux

(cetuximab)Orphan drugstandard

ImClone Systems Incorporated

Epidermal Growth Factor Receptor Antagonist [EPC]

12.1 Mechanism of Action The epidermal growth factor receptor (EGFR, HER1, c-ErbB-1) is a transmembrane glycoprotein that is a member of a subfamily o...

FDA label ↗

KEYTRUDA

(pembrolizumab)Orphan drugstandard

MSD International Business GmbH

Endoglycosidase [EPC]

12.1 Mechanism of Action Binding of the PD-1 ligands, PD-L1 and PD-L2, to the PD-1 receptor found on T cells, inhibits T cell proliferation and cytoki...

FDA label ↗

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Clinical Trial Landscape

120 active trials
10Phase 3
1Phase 4
51Phase 2
14Phase 1
12N/A
17Unknown
2PHASE2, PHASE3
5EARLY_PHASE1
8PHASE1, PHASE2
120Total recruiting
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Specialist Network

Top 6 by expertise

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