Rare aplastic anemia

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At a Glance

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Regulatory Watchboard

10 events
Nov 2024A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia

City of Hope Medical Center — PHASE1

TrialRECRUITING
Nov 2024Reduced Dose of Cyclophosphamide Combined With Standard Immunosuppressive Therapy to Treat Severe Aplastic Anemia

Institute of Hematology & Blood Diseases Hospital, China — PHASE2

TrialRECRUITING
Jul 2023Cyclophosphamide Added to Standard Immunosuppressive Therapy With Herombopag as Front-line Therapy in Patients With Severe Aplastic Anemia

Institute of Hematology & Blood Diseases Hospital, China — PHASE2

TrialACTIVE NOT RECRUITING
Feb 2023Rituximab for Serious Aplastic Anemia With Platelet Transfusion Refractoriness

Institute of Hematology & Blood Diseases Hospital, China — PHASE2

TrialRECRUITING
May 2020Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)

National Heart, Lung, and Blood Institute (NHLBI) — PHASE2

TrialRECRUITING
Nov 2018

Eltrombopag: FDA approved

PROMACTA is indicated in combination with standard immunosuppressive therapy for the first-line treatment of adult and pediatric patients 2 years and older with severe aplastic anemia.

FDAcompleted
Dec 2016Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

National Heart, Lung, and Blood Institute (NHLBI) — PHASE2

TrialACTIVE NOT RECRUITING
Jul 2012Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

National Heart, Lung, and Blood Institute (NHLBI) — PHASE1

TrialACTIVE NOT RECRUITING
Apr 2011Eltrombopag for Moderate Aplastic Anemia

National Heart, Lung, and Blood Institute (NHLBI) — PHASE2

TrialACTIVE NOT RECRUITING
Dec 2010Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

National Heart, Lung, and Blood Institute (NHLBI) — PHASE2

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

1 program

FINANCIAL LANDSCAPE SUMMARY

1

Total programs

1

Open now

Patient Assistance Programs1

ELTROMBOPAG

Dr. Reddy's Laboratories Inc.,

OpenContact for details

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Approved Treatments

3 FDA-approved

Eltrombopag

(ELTROMBOPAG OLAMINE)Orphan drug

Novadoz Pharmaceuticals LLC

Approved Nov 2018FDA label ↗

ELTROMBOPAG

(ELTROMBOPAG)standard

Dr. Reddy's Laboratories Inc.,

12.1 Mechanism of Action Eltrombopag is a TPO-receptor agonist that interacts with the transmembrane domain of the human TPO-receptor (also known as c...

FDA label ↗

Omisirge

(OMIDUBICEL-ONLV)Orphan drugstandard

Gamida Cell Inc.

12.1 Mechanism of Action OMISIRGE is a nicotinamide (NAM) modified allogeneic hematopoietic progenitor cell therapy derived from cord blood used as an...

FDA label ↗

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Clinical Trial Landscape

No active clinical trials currently recruiting for Rare aplastic anemia.
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Recent News & Research

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Specialist Network

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