Primary central nervous system lymphoma

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At a Glance

Live from database

Regulatory Watchboard

10 events
Apr 2026Methotrexate Early Toxicity Monitoring

Assistance Publique Hopitaux De Marseille — NA

TrialNOT YET RECRUITING
Mar 2026IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

Ono Pharmaceutical Co. Ltd — PHASE3

TrialRECRUITING
Feb 2026Thiotepa in Combination With Pirtobrutinib (a BTK Inhibitor) and Sintilimab (a PD-1 Inhibitor) for Frail or Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma

Zhejiang Cancer Hospital — PHASE2

TrialRECRUITING
Feb 2026PD-1 Inhibitor Combined With Rituximab, Methotrexate, and Orelabrutinib (PD-1i+RMO) for Newly Diagnosed PCNSL and SCNSL.

The First Affiliated Hospital with Nanjing Medical University — PHASE2

TrialRECRUITING
Jan 2026Zillion: Zanubrutinib Combined With Chemotherapy for Newly Diagnosed CNS Lymphoma

Ruijin Hospital — PHASE2

TrialNOT YET RECRUITING
Dec 2025A Multicenter Two-Cohort Study of Methotrexate, Rituximab, Sintilimab and Pirtobrutinib for Treatment-Naive PCNSL vs. Real-World Investigator-Selected Treatment (Observational Cohort)

Tongji Hospital — PHASE2

TrialRECRUITING
Nov 2025Anbalcabtagene Autoleucel in Relapsed/Refractory CNS Lymphoma

Hyungwoo Cho — PHASE2

TrialRECRUITING
Nov 2025A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company — PHASE2

TrialRECRUITING
Oct 2025Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL

Huashan Hospital — PHASE2, PHASE3

TrialNOT YET RECRUITING
Sep 2025Study of Epcoritamab in R/R Primary Diffuse Large B-cell Lymphoma of the CNS Treated With Lenalidomide and Rituximab

The Lymphoma Academic Research Organisation — PHASE2

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

FINANCIAL LANDSCAPE SUMMARY

0

Total programs

No financial assistance programs currently listed for Primary central nervous system lymphoma.
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Clinical Trial Landscape

71 active trials
3Phase 3
1Phase 4
28Phase 2
14Phase 1
5N/A
8Unknown
9PHASE1, PHASE2
2PHASE2, PHASE3
1EARLY_PHASE1
71Total recruiting
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Recent News & Research

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Specialist Network

Top 6 by expertise

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