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SIMPONI ARIA®: FDA approved
treatment of active polyarticular juvenile idiopathic arthritis (pJIA) in patients 2 years of age and older
Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
FINANCIAL LANDSCAPE SUMMARY
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Copay Assistance1
SIMPONI ARIA�
Janssen Research & Development, LLC
Patient Assistance Programs2
SIMPONI ARIA�
(golimumab)Orphan drugJanssen Research & Development, LLC
Tumor Necrosis Factor Blocker [EPC]
12.1 Mechanism of Action Golimumab is a human monoclonal antibody that binds to both the soluble and transmembrane bioactive forms of human TNFα. This...
Enbrel
(etanercept)Orphan drugstandardImmunex Corporation
Tumor Necrosis Factor Blocker [EPC]
12.1 Mechanism of Action TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. It plays an important rol...
Orencia
(abatacept)Orphan drugstandardBristol-Myers Squibb Co.
Selective T Cell Costimulation Modulator [EPC]
12.1 Mechanism of Action Abatacept, a selective costimulation modulator, inhibits T-cell (T lymphocyte) activation by binding to CD80 and CD86, thereb...
Actemra
(tocilizumab)Orphan drugstandardGenentech, Inc.
Interleukin-6 Receptor Antagonist [EPC]
12.1 Mechanism of Action Tocilizumab binds to both soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R), and has been shown to inhibit IL-6-m...
HUMIRA
(adalimumab)Orphan drugstandardAbbVie, Inc.
12.1 Mechanism of Action Adalimumab binds specifically to TNF-alpha and blocks its interaction with the p55 and p75 cell surface TNF receptors. Adalim...
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Takahiro Kakehi
Chugai Pharmaceutical
Yukiko Kimura, MD, M.D
Hackensack Meridian Health
📍 HACKENSACK, NJ
Sarah Ringold, MD, MD
Seattle Children's Hospital
📍 SEATTLE, WA
Shigeki Hashimoto, PhD
Abbott Japan Co.,Ltd
Pekka Lahdenne, MD, PhD
Hospital for Children and Adolescents in Helsinki University Central Hospital
Ragab K Elnaggar, PhD
Cairo University / Prince Sattam Bin Abdulaziz University
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