PIK3CA-related overgrowth syndrome

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At a Glance

Live from database

Regulatory Watchboard

10 events
Jun 2026Modulatory Effect of Prodigiosin or Pioglitazone on TIME and the Crosstalk to Immune-Checkpoint Protein(s)

Ain Shams University

TrialNOT YET RECRUITING
Nov 2025COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

University of North Carolina, Chapel Hill

TrialNOT YET RECRUITING
Oct 2025EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

Novartis Pharmaceuticals — PHASE2

TrialRECRUITING
Sep 2025Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment

Boston Medical Center — NA

TrialRECRUITING
Aug 2025The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System

Brooke Army Medical Center — NA

TrialNOT YET RECRUITING
Jul 2025UK ENcorafenib and BInimetinib Real-world Study in Melanoma

Pierre Fabre Ltd

TrialRECRUITING
Jul 2025Use of Airpod Pros as Assistive Technology

The University of Texas at Dallas — NA

TrialRECRUITING
Jun 2025A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation

Relay Therapeutics, Inc. — PHASE2

TrialRECRUITING
May 2025Implementing REmote SymPtom mOnitoring and maNagement (RESPONd)

University of Calgary — NA

TrialRECRUITING
Sep 2024Innovating Access to Novel Therapies Through Standardized Prospective Integration of Response Evaluations (IMPACT-INSPIRE)

National Cancer Centre, Singapore

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

1 program

FINANCIAL LANDSCAPE SUMMARY

1

Total programs

1

Open now

Patient Assistance Programs1

Vijoice

Novartis Pharmaceuticals Corporation

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Approved Treatments

1 FDA-approved

Vijoice

(alpelisib)Orphan drug

Novartis Pharmaceuticals Corporation

12.1 Mechanism of Action Alpelisib is an inhibitor of phosphatidylinositol-3-kinase (PI3K) with inhibitory activity predominantly against PI3Kα. Gain-...

Approved Apr 2024FDA label ↗

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Clinical Trial Landscape

13 active trials
5Phase 2
1N/A
6Unknown
1PHASE1, PHASE2
13Total recruiting
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Recent News & Research

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Specialist Network

Top 4 by expertise

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