Osteosarcoma

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At a Glance

Live from database

2FDA treatments

33Recruiting trials

Regulatory Watchboard

10 events

Apr 2026Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

Milton S. Hershey Medical Center — PHASE2

TrialNOT YET RECRUITING

Mar 2026A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

Memorial Sloan Kettering Cancer Center — PHASE2

TrialRECRUITING

Mar 2026Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma

Emory University — PHASE1

TrialRECRUITING

Feb 2026Musculoskeletal Cancers Remote Monitoring and Care

Case Comprehensive Cancer Center — NA

TrialRECRUITING

Feb 2026Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma

St. Jude Children's Research Hospital — PHASE2

TrialNOT YET RECRUITING

Jan 2026Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma

Emory University — PHASE1

TrialRECRUITING

Jan 2026Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial

Fred Hutchinson Cancer Center — PHASE1

TrialRECRUITING

Oct 2025A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

Society of Interventional Oncology

TrialRECRUITING

Sep 2025T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.

M.D. Anderson Cancer Center — PHASE1

TrialRECRUITING

Aug 2025Envafolimab Combined With Neoadjuvant Chemotherapy Treat Stage IIb Resectable Osteosarcoma Patients

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine — PHASE2

TrialNOT YET RECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

2 programs

FINANCIAL LANDSCAPE SUMMARY

2

Total programs

2

Open now

Patient Assistance Programs2

Methotrexate

Lederle Laboratories

OpenContact for details

Fusilev

Acrotech Biopharma LLC

OpenContact for detailsApply ↗

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Approved Treatments

2 FDA-approved

Leucovorin calcium

(Leucovorin)Orphan drugstandard

Immunex Corporation

Fusilev

(levoleucovorin)Orphan drugstandard

Acrotech Biopharma LLC

12.1 Mechanism of Action High-Dose Methotrexate Therapy Levoleucovorin is the pharmacologically active isomer of 5-formyl tetrahydrofolic acid. Levole...

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Clinical Trial Landscape

33 active trials

1Phase 3

11Phase 2

5Phase 1

1N/A

8Unknown

1EARLY_PHASE1

6PHASE1, PHASE2

33Total recruiting

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Recent News & Research

No recent news articles indexed yet for Osteosarcoma.
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Specialist Network

Top 6 by expertise

Roberto Luksch, MD

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

📍 SAINT CLAIR SHORES, MI

Score 102 trials

Sant P Chawla, MD, M.D

Sarcoma Oncology Research Center

📍 SANTA MONICA, CA

Score 95 trials

Katherine A Janeway, M.D

Children's Oncology Group

📍 BOSTON, MA

Score 82 trials7 pubs

Meredith S Irwin

Children's Oncology Group

📍 CINCINNATI, OH

Andrea T Franson, MD

Children's Oncology Group

📍 ANN ARBOR, MI

Minal Barve, MD, M.D

Mary Crowley Cancer Research Centers

📍 DALLAS, TX

Score 74 trials

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