OBSOLETE: Inherited retinal disorder

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At a Glance

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Regulatory Watchboard

10 events
Mar 2026The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions in Adolescent Patients With Retinitis Pigmentosa

Sheba Medical Center — PHASE1, PHASE2

TrialNOT YET RECRUITING
Feb 2026A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)

Octant, Inc. — PHASE1, PHASE2

TrialRECRUITING
Jul 2025A Study of LX107 Gene Therapy in AIPL1-IRD Patients

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine — EARLY_PHASE1

TrialRECRUITING
Jul 2025A Multicenter, Randomized, Double-Blind, Controlled Clinical Study of Minocycline for the Treatment of Retinitis Pigmentosa

Zhongshan Ophthalmic Center, Sun Yat-sen University — PHASE3

TrialNOT YET RECRUITING
Jun 2025A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001

PYC Therapeutics — PHASE1, PHASE2

TrialRECRUITING
May 2025The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

University of Rochester — PHASE1

TrialRECRUITING
Apr 2025An Open-label, Dose-ascending Study of IGT001 for Retinitis Pigmentosa

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine — PHASE1

TrialRECRUITING
Mar 2025Prospective Exploratory Cohort Study on Ganglion Cell Degeneration in Retinitis Pigmentosa Patients

University Medical Center Goettingen

TrialENROLLING BY INVITATION
Jun 2024A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa

Ocugen — PHASE3

TrialACTIVE NOT RECRUITING
Jun 2024MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

PYC Therapeutics — PHASE1

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

FINANCIAL LANDSCAPE SUMMARY

0

Total programs

No financial assistance programs currently listed for OBSOLETE: Inherited retinal disorder.
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Approved Treatments

1 FDA-approved

LUXTURNA

(voretigene neparvovec-rzyl)Orphan drugstandard

Spark Therapeutics, Inc.

12.1 Mechanism of Action LUXTURNA is designed to deliver a normal copy of the gene encoding the human retinoid isomerohydrolase RPE65 (RPE65) to cells...

FDA label ↗

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Clinical Trial Landscape

24 active trials
2Phase 3
7Phase 1
1N/A
6Unknown
3EARLY_PHASE1
5PHASE1, PHASE2
24Total recruiting
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