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HUMIRA
(adalimumab)Orphan drugstandardAbbVie, Inc.
12.1 Mechanism of Action Adalimumab binds specifically to TNF-alpha and blocks its interaction with the p55 and p75 cell surface TNF receptors. Adalim...
Enbrel
(etanercept)Orphan drugstandardImmunex Corporation
Tumor Necrosis Factor Blocker [EPC]
12.1 Mechanism of Action TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. It plays an important rol...
SIMPONI ARIA�
(golimumab)Orphan drugstandardJanssen Research & Development, LLC
Tumor Necrosis Factor Blocker [EPC]
12.1 Mechanism of Action Golimumab is a human monoclonal antibody that binds to both the soluble and transmembrane bioactive forms of human TNFα. This...
Remicade
(infliximab)Orphan drugstandardJanssen Biotech, Inc.
Tumor Necrosis Factor Blocker [EPC]
12.1 Mechanism of Action Infliximab neutralizes the biological activity of TNFα by binding with high affinity to the soluble and transmembrane forms o...
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