Neurotrophic keratopathy

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At a Glance

Live from database

1FDA treatments

10Recruiting trials

Regulatory Watchboard

10 events

Mar 2026Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic Keratopathy Patients With Tear Deficiency

University of South Florida — PHASE4

TrialRECRUITING

Aug 2025Corneal Neurotization vs. Cenergermin for Neurotrophic Keratitis: A Pilot Study

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's — NA

TrialNOT YET RECRUITING

Jul 2025A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis

Krystal Biotech, Inc. — PHASE1, PHASE2

TrialRECRUITING

Jun 2025A Phase II Study of STSP-0902 Ophthalmic Solution in Patients With Neurotrophic Keratitis

Staidson (Beijing) Biopharmaceuticals Co., Ltd — PHASE2

TrialRECRUITING

Feb 2025Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease

Toyos Clinic — PHASE4

TrialRECRUITING

Oct 2024A Study of STSP-0902 Ophthalmic Solution in Healthy Subjects

Staidson (Beijing) Biopharmaceuticals Co., Ltd — PHASE1

TrialACTIVE NOT RECRUITING

Jul 2024Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis

BRIM Biotechnology Inc. — PHASE2

TrialRECRUITING

Apr 2023Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

ReGenTree, LLC — PHASE3

TrialRECRUITING

Jan 2023DOMPE -MT Neurotrophic Keratitis

Toyos Clinic — PHASE4

TrialACTIVE NOT RECRUITING

Nov 2020Autologous Platelet-rich Plasma (APRP) in the Treatment of Neurotrophic Keratopathy

Universidad Autonoma de Nuevo Leon — NA

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

1 program

FINANCIAL LANDSCAPE SUMMARY

1

Total programs

1

Open now

Patient Assistance Programs1

Oxervate

Dompe S.p.A.

OpenContact for details

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Approved Treatments

1 FDA-approved

Oxervate

(cenegermin-bkbj)Orphan drug

Dompe S.p.A.

Recombinant Human Nerve Growth Factor [EPC]

12.1 Mechanism of Action Nerve growth factor is an endogenous protein involved in the differentiation and maintenance of neurons, which acts through s...

Approved Aug 2018FDA label ↗

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Clinical Trial Landscape

10 active trials

1Phase 3

3Phase 4

2Phase 2

1Phase 1

1N/A

1Unknown

1PHASE1, PHASE2

10Total recruiting

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Recent News & Research

No recent news articles indexed yet for Neurotrophic keratopathy.
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Specialist Network

Top 6 by expertise

Ali R Djalilian, MD

University of Illinois at Chicago

Score 391 trial1 pub

Weiyun Shi, Ph.D

Shandong First Medical University Affiliated Eye Hospital

Score 121 trial

Leonardo Mastropasqua, Professor

Ophtalmology Clinic, G. d'Annunzio University

Score 102 trials

Ting Wang, Ph.D

Shandong First Medical University Affiliated Eye Hospital

Flavio Mantelli, MD, PhD

Dompé farmaceutici S.p.A., Milan

Score 74 trials

Laichun Lu, Ph.D

Beijing Tongren Hospital

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