Multiple myeloma

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At a Glance

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Regulatory Watchboard

10 events
Jul 2026Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma

Natalie Callander — PHASE1, PHASE2

TrialNOT YET RECRUITING
May 2026Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel)

Washington University School of Medicine — PHASE1

TrialNOT YET RECRUITING
May 2026Identifying Effective and Cost-Conscious Maintenance Daratumumab Dosing

Eden Biltibo — PHASE2

TrialNOT YET RECRUITING
Apr 2026Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse

National Cancer Institute (NCI) — PHASE2

TrialNOT YET RECRUITING
Apr 2026ELDORADO: Elranatamab Versus Daratumumab in Combination With RVd Lite for Newly Diagnosed Transplant Ineligible/Deferred Multiple Myeloma

Massachusetts General Hospital — PHASE2

TrialNOT YET RECRUITING
Apr 2026A Phase I Study of SHR-3836 in Patients With Multiple Myeloma

Shanghai Hengrui Pharmaceutical Co., Ltd. — PHASE1

TrialNOT YET RECRUITING
Mar 2026A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)

Regeneron Pharmaceuticals — PHASE3

TrialNOT YET RECRUITING
Mar 2026A Trial to Study if REGN17372 in Combination With Linvoseltamab is Tolerable for Adult Participants With Relapsed/Refractory Multiple Myeloma

Regeneron Pharmaceuticals — PHASE1, PHASE2

TrialNOT YET RECRUITING
Mar 2026OZURDEX: New indication approved
FDAcompleted
Mar 2026TECVAYLI: New indication approved
FDAcompleted

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

23 programs

FINANCIAL LANDSCAPE SUMMARY

23

Total programs

23

Open now

23

Copay cards

Copay Assistance23

Abecma

Celgene Corporation, a Bristol-Myers Squibb Company

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Melphalan

Sagent

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Thalomid

Celgene

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Darzalex Faspro

Janssen

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Sarclisa

Sanofi

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Carvykti

Janssen Research & Development, LLC

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Blenrep

GlaxoSmithKline

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TALVEY

Janssen

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EMPLICITI

Bristol Myers Squibb

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Bortezomib

Takeda

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Farydak

zr pharma& GmbH

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TECVAYLI

Janssen

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KYPROLIS

Amgen

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Pomalidomide

Bristol Myers Squibb

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Lenalidomide

Bristol Myers Squibb

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Mozobil

Sanofi

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LYNOZYFIC

Unknown

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XPOVIO

Karyopharm

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PLERIXAFOR

Sanofi

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APHEXDA

BioLineRx

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Elrexfio

Pfizer

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VELCADE

Takeda

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NINLARO

Takeda

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View all support programs on disease page →

Approved Treatments

8 FDA-approved

Lynozyfic

(linvoseltamab-gcpt)Orphan drug

Regeneron Pharmaceuticals, Inc.

12.1 Mechanism of Action Linvoseltamab-gcpt is a bispecific T-cell engaging antibody that binds to the CD3 receptor expressed on the surface of T-cell...

Approved Jul 2025FDA label ↗

Abecma

(idecabtagene vicleucel)Orphan drug

Celgene Corporation, a Bristol-Myers Squibb Company

12.1 Mechanism of Action ABECMA is a chimeric antigen receptor (CAR)-positive T cell therapy targeting B-cell maturation antigen (BCMA), which is expr...

Approved Apr 2024FDA label ↗

Talvey

(talquetamab-tgvs)Orphan drug

Janssen Biotech, inc.

12.1 Mechanism of Action Talquetamab-tgvs is a bispecific T-cell engaging antibody that binds to the CD3 receptor expressed on the surface of T-cells ...

Approved Aug 2023FDA label ↗

Tecvayli

(teclistamab-cqyv)Orphan drug

Janssen Biotech, Inc.

12.1 Mechanism of Action Teclistamab-cqyv is a bispecific T-cell engaging antibody that binds to the CD3 receptor expressed on the surface of T-cells ...

Approved Oct 2022FDA label ↗

Carvykti

(ciltacabtagene autoleucel)Orphan drug

Janssen Research & Development, LLC

12.1 Mechanism of Action CARVYKTI is a BCMA-directed, genetically modified autologous T cell immunotherapy, which involves reprogramming a patient's o...

Approved Feb 2022FDA label ↗

Kyprolis

(carfilzomib)Orphan drug

Onyx Therapeutics, Inc.

Proteasome Inhibitor [EPC]

12.1 Mechanism of Action Carfilzomib is a tetrapeptide epoxyketone proteasome inhibitor that irreversibly binds to the N-terminal threonine-containing...

Approved Aug 2020FDA label ↗

BLENREP

(belantamab mafodotin-blmf)Orphan drug

GlaxoSmithKline Intellectual Property Development Ltd.

12.1 Mechanism of Action Belantamab mafodotin‑blmf is an antibody‑drug conjugate (ADC). The antibody component is an afucosylated IgG1 directed agains...

Approved Aug 2020FDA label ↗

Sarclisa

(isatuximab-irfc)Orphan drug

Sanofi-Aventis U.S. LLC

CD38-directed Cytolytic Antibody [EPC]

12.1 Mechanism of Action Isatuximab-irfc is an IgG1-derived monoclonal antibody that binds to CD38 expressed on the surface of hematopoietic and tumor...

Approved Mar 2020FDA label ↗

View full treatment details on disease page →

Clinical Trial Landscape

145 active trials
21Phase 3
2Phase 4
52Phase 2
15Phase 1
7N/A
30Unknown
11PHASE1, PHASE2
3PHASE2, PHASE3
4EARLY_PHASE1
145Total recruiting
Search clinical trials for Multiple myeloma

Recent News & Research

6 articles
Expert opinion on biological therapyApr 22, 2026

A review of the clinical efficacy of monoclonal antibody (mAb)-based therapies for relapsed/refractory multiple myeloma (RRMM).

Monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs) are among the backbones of treatment for relapsed/refractory multiple myeloma (RRMM). Beyond current standard-of-care regimens, the rol...

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Leukemia & lymphomaApr 21, 2026

Targeting the FOXM1/BUB1B signaling network in multiple myeloma: mechanistic insights and therapeutic potential.

Multiple myeloma (MM) is a plasma cell cancer characterized by genomic instability and drug resistance. The FOXM1 transcription factor and the BUB1B kinase are pivotal drivers of this malignancy. FOXM...

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American journal of hematologyApr 21, 2026

Integrating Recent Evidence and Expert Perspectives Into the Management of Multiple Myeloma: Consensus Recommendations From the 2025 Bridging the Gaps Conference.

The rapid expansion of therapeutic options for multiple myeloma (MM) has created uncertainty regarding optimal sequencing and clinical application. To address gaps in evidence, the 2025 Bridging the G...

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Seminars in hematologyApr 21, 2026

Targeted immunoPET imaging of multiple myeloma.

Current standard of care methods of imaging multiple myeloma disease burden are suboptimal. For example, fluorodeoxyglucose-(FDG)-PET/CT may fail to detect up to 50% of myeloma lesions. Immunologicall...

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International journal of hematologyApr 15, 2026

Talquetamab in Japanese patients with relapsed/refractory multiple myeloma in the MonumenTAL-1 study.

Talquetamab is the first G protein-coupled receptor family C group 5 member D (GPRC5D) × CD3 bispecific antibody approved for relapsed/refractory multiple myeloma (RRMM). We report ...

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BloodApr 2, 2026

Genomic mechanisms of resistance to venetoclax in multiple myeloma with t(11;14)(CCND1;IGH).

Multiple myeloma (MM) with t(11;14)(CCND1;IGH) remains the only subset sensitive to the BCL2 inhibitor venetoclax. However, not all patients with t(11;14)(CCND1;IGH) respond to treatment, and some pro...

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Specialist Network

Top 6 by expertise

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