Langerhans cell histiocytosis

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At a Glance

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Regulatory Watchboard

10 events
Jun 2026Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone Lesions

West China Second University Hospital — NA

TrialRECRUITING
Feb 2026Modified LCH-III Regimen With or Without Luvometinib for Multisystem Pediatric Langerhans Cell Histiocytosis

West China Second University Hospital — NA

TrialRECRUITING
Aug 2025Efficacy and Safety of XTD Regimen (Selinexor, Thalidomide and Dexamethasone) in Adult Patients With Relapsed/Refractory LCH

Cancer Institute and Hospital, Chinese Academy of Medical Sciences — PHASE2

TrialACTIVE NOT RECRUITING
Jun 2025Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children

West China Second University Hospital — PHASE2

TrialRECRUITING
Apr 2025Efficacy and Safety of the RD Regimen(Lenalidomide, Dexamethasone) for Rosai-Dorfman Disease

Cancer Institute and Hospital, Chinese Academy of Medical Sciences — PHASE2

TrialRECRUITING
Apr 2025Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH

Cancer Institute and Hospital, Chinese Academy of Medical Sciences — PHASE2

TrialRECRUITING
Feb 2025Adebrelimab Combined With Trametinib in the Treatment of Refractory Recurrent Langerhans Cell Histiocytosis in Children and Adolescents

Second Affiliated Hospital of Wenzhou Medical University — PHASE1

TrialENROLLING BY INVITATION
Jun 2024Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib

Cook Children's Health Care System — PHASE2

TrialRECRUITING
Mar 2024A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

National Cancer Institute (NCI) — PHASE2

TrialRECRUITING
Mar 2024Biomarkers for Diagnostic, Prognostic and of Response to Treatment in Adult Langerhans Cell Histiocytosis

Assistance Publique - Hôpitaux de Paris

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

FINANCIAL LANDSCAPE SUMMARY

0

Total programs

No financial assistance programs currently listed for Langerhans cell histiocytosis.
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Clinical Trial Landscape

17 active trials
3Phase 3
9Phase 2
1Phase 1
2N/A
1Unknown
1PHASE2, PHASE3
17Total recruiting
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