IgG4-related disease

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At a Glance

Live from database

Regulatory Watchboard

10 events
Apr 2026Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Inebilizumab in Pediatric Participants With IgG4-RD

Amgen — PHASE2

TrialNOT YET RECRUITING
Jan 2026Study to Assess Safety, Efficacy and Persistence of ACE1831, in Subjects With IgG4-Related Disease

Acepodia Biotech, Inc. — PHASE1, PHASE2

TrialRECRUITING
Dec 2025An Exploratory Clinical Study on the Safety and Efficacy of CD19/BCMA CAR-NK in the Treatment of Relapsed and Refractory IgG4-related Disease

Changhai Hospital — EARLY_PHASE1

TrialNOT YET RECRUITING
Nov 2025A Study of Efgartigimod in Patients With IgG4-Related Disease

Stanford University — PHASE2

TrialRECRUITING
Sep 2025A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

Sanofi — PHASE3

TrialRECRUITING
Sep 2025Exploratory Study of Anti-BCMA-CD19 CAR-T Cell Therapy in Relapsed or Refractory IgG4-Related Disease

Chinese PLA General Hospital — PHASE2

TrialRECRUITING
Jul 2025A Randomized Controlled Study of the Efficacy and Safety of Lenalidomide in the Treatment of Active IgG4-related Disease

Peking Union Medical College Hospital — PHASE2, PHASE3

TrialRECRUITING
May 2025A Study on the Effect of MRD Detected by FAPI PET / CT on the Recurrence of IgG4-RD

Luo Yaping — NA

TrialRECRUITING
Mar 2025Adaptive and Trained Immunity in the Pathogenesis of IgG4-Related Disease

IRCCS San Raffaele

TrialACTIVE NOT RECRUITING
Nov 2024Key Mechanisms of Abnormal T Cell Activation and Differentiation in IgG4-Related Ophthalmic Disease

Peking University Third Hospital

TrialNOT YET RECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

2 programs

FINANCIAL LANDSCAPE SUMMARY

2

Total programs

2

Open now

Patient Assistance Programs2

Uplizna

Horizon Therapeutics USA, Inc.

OpenContact for detailsApply ↗

Leustatin Injection

R. W. Johnson Pharmaceutical Research Institute

OpenContact for details

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Approved Treatments

1 FDA-approved

Uplizna

(INEBILIZUMAB)Orphan drugstandard

Horizon Therapeutics USA, Inc.

CD19-directed Cytolytic Antibody [EPC]

12.1 Mechanism of Action The mechanism by which inebilizumab-cdon exerts its therapeutic effects in NMOSD, IgG4-RD, and gMG is presumed to involve bin...

FDA label ↗

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Clinical Trial Landscape

16 active trials
3Phase 3
2Phase 2
4N/A
3Unknown
2EARLY_PHASE1
1PHASE2, PHASE3
1PHASE1, PHASE2
16Total recruiting
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Recent News & Research

No recent news articles indexed yet for IgG4-related disease.
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Specialist Network

Top 6 by expertise

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