Glycogen storage disease due to acid maltase deficiency

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At a Glance

Live from database

Regulatory Watchboard

10 events
Mar 2026BERKLEY AND JENSEN OMEPRAZOLE: New indication approved
FDAcompleted
Mar 2026Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease

University of Missouri-Columbia — NA

TrialRECRUITING
Mar 2026A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease

Denali Therapeutics Inc. — PHASE1

TrialNOT YET RECRUITING
Feb 2026A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late Onset Pompe Disease (PROGRESS-GT LOPD)

AskBio Inc — PHASE1, PHASE2

TrialRECRUITING
Oct 2025Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

Shionogi — PHASE2

TrialRECRUITING
May 2025China Post-approval Commitment (PAC) Study of Avalglucosidase Alfa in Participants With IOPD

Genzyme, a Sanofi Company — PHASE4

TrialRECRUITING
Dec 2024Rare Glycogen Storage Diseases Natural History Study

Duke University

TrialRECRUITING
Nov 2024A Clinical Trial Evaluating the Safety and Efficacy of a New Light Combination Therapy Addressing Intermediate AMD

Oculox Technologies SA — NA

TrialRECRUITING
Oct 2024Treatment Frequency Reduction in Pompe Disease

Erasmus Medical Center — PHASE4

TrialNOT YET RECRUITING
Apr 2024Evaluation of the Safety and Efficacy of Late-onset Pompe Disease Gene Therapy Drug

GeneCradle Inc — PHASE1, PHASE2

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

2 programs

FINANCIAL LANDSCAPE SUMMARY

2

Total programs

2

Open now

2

Copay cards

Copay Assistance2

Pombiliti and Opfolda

Amicus Therapeutics, Inc.

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Myozyme

Genzyme Corporation

OpenContact for details

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Approved Treatments

4 FDA-approved

Pombiliti and Opfolda

(cipaglucosidase alfa-atga and miglustat)Orphan drug

Amicus Therapeutics, Inc.

Approved Sep 2023

Nexviazyme

(AVALGLUCOSIDASE ALFA-NGPT)Orphan drug

Genzyme Corporation

Approved Aug 2021FDA label ↗

Myozyme

(Recombinant human acid alpha-glucosidase; alglucosidase alfa)Orphan drug

Genzyme Corporation

Approved Apr 2006

Omeprazole

(OMEPRAZOLE)Orphan drugstandard

PD-Rx Pharmaceuticals, Inc.

Proton Pump Inhibitor [EPC]

12.1 Mechanism of Action Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretio...

FDA label ↗

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Clinical Trial Landscape

26 active trials
3Phase 3
2Phase 4
2Phase 2
1Phase 1
2N/A
10Unknown
5PHASE1, PHASE2
1EARLY_PHASE1
26Total recruiting
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Recent News & Research

2 articles
Molecular Genetics and MetabolismSep 20, 2025

Pompe Disease Newborn Screening Shows 60% Faster Treatment

States implementing Pompe newborn screening reported 60% reduction in time to treatment initiation.

Read ↗
HHSAug 15, 2025

Newborn Screening Expands to Include More Rare Diseases

The Advisory Committee recommended adding Duchenne MD and Pompe disease to the Recommended Uniform Screening Panel.

Read ↗

Browse all Glycogen storage disease due to acid maltase deficiency news →

Specialist Network

Top 6 by expertise

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