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Iwilfin: FDA approved
to reduce the risk of relapse in adult and pediatric patients with high-risk neuroblastoma (HRNB) who have demonstrated at least a partial response to prior multiagent, multimodality therapy including anti-GD2 immunotherapy
National Cancer Institute (NCI)
DANYELZA®: FDA approved
in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), for the treatment of pediatric patients 1 year of age and older and adult patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow who have demonstrated a partial response, minor response, or stable disease to prior therapy
Unituxin: FDA approved
For use in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2) and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy
AdreView: FDA approved
To be used in the detection of primary or metastatic pheochromocytomas or neuroblastomas as an adjunct to other diagnostic tests
Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
FINANCIAL LANDSCAPE SUMMARY
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Patient Assistance Programs2
Iwilfin
USWM, LLC
AdreView
GE Healthcare, Inc.
Iwilfin
(eflornithine)Orphan drugUSWM, LLC
12.1 Mechanism of Action Eflornithine is an irreversible inhibitor of the enzyme ornithine decarboxylase (ODC), the first and rate-limiting enzyme in ...
Unituxin
(dinutuximab)Orphan drugUnited Therapeutics Corporation
Glycolipid Disialoganglioside-directed Antibody [EPC]
12.1 Mechanism of Action Dinutuximab binds to the glycolipid GD2. This glycolipid is expressed on neuroblastoma cells and on normal cells of neuroecto...
Charalampos Floudas, M.D., M.D
National Cancer Institute (NCI)
📍 BETHESDA, MD
Marylin J. Dodd, RN, PhD, MHC
University of California, San Francisco
📍 SOUTH BEND, IN
Shivaani Kummar, MD
NCI - Medical Oncology Branch
📍 PORTLAND, OR
Monica Loghin, M.D
M.D. Anderson Cancer Center
📍 HOUSTON, TX
Paul O'Brien
Medical University of South Carolina
Hassan Arshad, MD
Roswell Park Cancer Institute
📍 CHICAGO, IL