Erdheim-Chester disease

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At a Glance

Live from database

Regulatory Watchboard

10 events
Dec 2024ECD-Score: a Study on Erdheim-Chester Disease

Meyer Children's Hospital IRCCS

TrialRECRUITING
Sep 2022Histiocytic Disorder Follow-up Study

University of Alabama at Birmingham

TrialRECRUITING
Oct 2021In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

Memorial Sloan Kettering Cancer Center — EARLY_PHASE1

TrialRECRUITING
Apr 2021Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Carl Allen — PHASE2

TrialRECRUITING
Jun 2019Supportive Care Needs of Caregivers of People With Erdheim-Chester Disease and Other Histiocytic Diseases

Memorial Sloan Kettering Cancer Center

TrialRECRUITING
Nov 2017Zelboraf: FDA approved

Treatment of patients with Erdheim-Chester Disease with BRAF V600 mutation

FDAcompleted
Oct 2017Registry for Patients With Erdheim-Chester Disease and Other Histiocytoses

Memorial Sloan Kettering Cancer Center

TrialRECRUITING
Apr 2017A Study of Memory, Thinking, and Brain Imaging in Adults With Histiocytosis

Memorial Sloan Kettering Cancer Center

TrialACTIVE NOT RECRUITING
Aug 2015Lenalidomide for Adult Histiocyte Disorders

Dana-Farber Cancer Institute — PHASE2

TrialACTIVE NOT RECRUITING
Oct 2014International Rare Histiocytic Disorders Registry (IRHDR)

The Hospital for Sick Children

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

1 program

FINANCIAL LANDSCAPE SUMMARY

1

Total programs

1

Open now

Patient Assistance Programs1

Zelboraf

Genentech, Inc.

OpenContact for detailsApply ↗

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Approved Treatments

2 FDA-approved

Zelboraf

(VEMURAFENIB)Orphan drug

Genentech, Inc.

Kinase Inhibitor [EPC]

12.1 Mechanism of Action Vemurafenib is a low molecular weight, orally available inhibitor of some mutated forms of BRAF serine- threonine kinase, inc...

Approved Nov 2017FDA label ↗

XARELTO

(RIVAROXABAN)standard

Janssen Pharmaceuticals, Inc.

Factor Xa Inhibitor [EPC]

12.1 Mechanism of Action XARELTO is a selective inhibitor of FXa. It does not require a cofactor (such as Anti-thrombin III) for activity. Rivaroxaban...

FDA label ↗

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Clinical Trial Landscape

8 active trials
2Phase 2
5Unknown
1EARLY_PHASE1
8Total recruiting
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Recent News & Research

No recent news articles indexed yet for Erdheim-Chester disease.
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Specialist Network

Top 6 by expertise

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