Diffuse large B-cell lymphoma

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At a Glance

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Regulatory Watchboard

10 events
Dec 2026Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

City of Hope Medical Center — PHASE2

TrialNOT YET RECRUITING
Jun 2026A Phase 1/2 Study of T-cell Expressing a Novel CD19 Chimeric-Antigen Receptor (SHB-02-CD19) in Patients With CD19-expressing B-cell Malignancies

Sheba Medical Center — PHASE1, PHASE2

TrialNOT YET RECRUITING
Apr 2026Glofitamab as a Bridge to and/or Consolidation Post Autologous Stem Cell Transplant in Patients With Relapsed B Cell Lymphomas

American University of Beirut Medical Center — PHASE2

TrialNOT YET RECRUITING
Apr 2026Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas

Abramson Cancer Center at Penn Medicine — PHASE1

TrialNOT YET RECRUITING
Apr 2026Characterization of Primary Central Nervous System Diffuse Large B Cell Lymphoma (PCNS-DLBCL) by Multiomic Approach

International Extranodal Lymphoma Study Group (IELSG)

TrialNOT YET RECRUITING
Apr 2026Phase Ib/II Study of Polatuzumab Vedotin in Combination With Rituximab and Chidamide in Newly Diagnosed Elderly Patients With Double-Expressor DLBCL

Sun Yat-sen University — PHASE1, PHASE2

TrialNOT YET RECRUITING
Mar 2026A Study to Evaluate MTM-H-001 Injection in Adult Participants With Relapsed or Refractory B-cell Malignancies

Cancer Institute and Hospital, Chinese Academy of Medical Sciences — NA

TrialNOT YET RECRUITING
Feb 2026ZYNLONTA: New indication approved
FDAcompleted
Jan 2026CRP Regimen in Treating Elderly Patients With Previously Untreated Double-Positive DLBCL

Tianjin Medical University Cancer Institute and Hospital — PHASE2

TrialRECRUITING
Jan 2026ZYNLONTA: New indication approved
FDAcompleted

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

5 programs

FINANCIAL LANDSCAPE SUMMARY

5

Total programs

5

Open now

5

Copay cards

Copay Assistance5

Rituxan Hycela

Genentech

OpenContact for detailsApply ↗

POLIVY

Genentech

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MONJUVI

Incyte

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EPKINLY

Genmab

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ZYNLONTA

ADC Therapeutics

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Approved Treatments

4 FDA-approved

Zynlonta

(loncastuximab tesirine-lpyl)Orphan drug

ADC Therapeutics SA

12.1 Mechanism of Action Loncastuximab tesirine-lpyl is an antibody-drug conjugate (ADC) targeting CD19. The monoclonal IgG1 kappa antibody component ...

Approved Apr 2021FDA label ↗

MONJUVI

(tafasitamab-cxix)Orphan drug

Incyte Corporation

12.1 Mechanism of Action Tafasitamab-cxix is an Fc-modified monoclonal antibody that binds to CD19 antigen expressed on the surface of pre-B and matur...

Approved Jul 2020FDA label ↗

Rituxan

(rituximab)Orphan drugstandard

Genentech, Inc.

Endoglycosidase [EPC]

12.1 Mechanism of Action Rituximab is a monoclonal antibody that targets the CD20 antigen expressed on the surface of pre-B and mature B-lymphocytes. ...

FDA label ↗

Rituxan SC

(rituximab and recombinant human hyaluronidase)Orphan drugstandard

Genentech, Inc.

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Clinical Trial Landscape

83 active trials
11Phase 3
33Phase 2
13Phase 1
6N/A
7Unknown
11PHASE1, PHASE2
2PHASE2, PHASE3
83Total recruiting
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Specialist Network

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