Desmoid tumor

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At a Glance

Live from database

1FDA treatments

18Recruiting trials

Regulatory Watchboard

10 events

Mar 2026OGSIVEO: New indication approved

FDAcompleted

Sep 2025Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

SpringWorks Therapeutics, Inc. — PHASE4

TrialRECRUITING

Aug 2025A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)

SpringWorks Therapeutics, Inc. — PHASE2

TrialRECRUITING

Jul 2025Treatment of Desmoid Fibromatosis With Arterial Embolization

Istituto Ortopedico Rizzoli

TrialRECRUITING

May 2025Immunological Phenotype of Desmoid-fibromatosis-affected Patients.

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

TrialRECRUITING

Nov 2024Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical Study

M.D. Anderson Cancer Center — PHASE2

TrialRECRUITING

Oct 2024Electrochemotherapy for Desmoid Tumors

Istituto Ortopedico Rizzoli

TrialRECRUITING

Sep 2024PRISM for Depression and Anxiety in Young Adults With Cancer

Dana-Farber Cancer Institute — NA

TrialACTIVE NOT RECRUITING

Apr 2024A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors

Blokhin's Russian Cancer Research Center — NA

TrialNOT YET RECRUITING

Mar 2024Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting

University Hospital, Strasbourg, France — NA

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

1 program

FINANCIAL LANDSCAPE SUMMARY

1

Total programs

1

Open now

Patient Assistance Programs1

Ogsiveo

SpringWorks Therapeutics (EMD Serono / Merck KGaA)

OpenContact for detailsApply ↗

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Approved Treatments

1 FDA-approved

Ogsiveo

(nirogacestat)Orphan drug

SpringWorks Therapeutics (EMD Serono / Merck KGaA)

Gamma Secretase Inhibitor [EPC]

12.1 Mechanism of Action Nirogacestat is a gamma secretase inhibitor that blocks proteolytic activation of the Notch receptor. When dysregulated, Notc...

Approved Nov 2023FDA label ↗

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Clinical Trial Landscape

18 active trials

1Phase 4

5Phase 2

5N/A

6Unknown

1PHASE2, PHASE3

18Total recruiting

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Recent News & Research

No recent news articles indexed yet for Desmoid tumor.
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Specialist Network

Top 6 by expertise

Bernd Kasper, MD

Mannheim University Medical Center

Score 361 trial

Douglas S Hawkins

Children's Oncology Group

📍 Birmingham, Alabama

Score 242 trials17 pubs

Nicolas PENEL, PhD

Centre Oscar Lambret

Score 231 trial

Hyo Song Kim

Severance Hospital, Yonsei University Health System

Score 211 trial925 pubs

Mrinal Gounder, MD, M.D

MSKCC

📍 NEW YORK, NY

Score 183 trials

Aaron R Weiss, DO

MaineHealth

Score 131 trial3 pubs

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