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Valchlor: FDA approved
Topical treatment of Stage 1A and 1B mycosis fungoides-type cutaneous T-cell lymphoma in patients who have received prior skin-directed therapy.
Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
FINANCIAL LANDSCAPE SUMMARY
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Valchlor
(meclorethamine)Orphan drugHelsinn Birex Pharmaceuticals Ltd.
Alkylating Drug [EPC]
12.1 Mechanism of Action Mechlorethamine, also known as nitrogen mustard, is an alkylating agent which inhibits rapidly proliferating cells.
Dyural 80-Lm
(METHYLPREDNISOLONE ACETATE, LIDOCAINE HYDROCHLORIDE, BUPIVACAINE HYDROCHLORIDE, POVIDINE IODINE, ISOPROPYL ALCOHOL)Orphan drugstandardAdvanced Rx Pharmacy of Tennessee, LLC
12.1 Mechanism of Action Bupivacaine blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical...
Methotrexate
(Methotrexate sodium)Orphan drugstandardLederle Laboratories
12.1 Mechanism of Action Methotrexate inhibits dihydrofolic acid reductase. Dihydrofolates must be reduced to tetrahydrofolates by this enzyme before ...
Adcetris
(brentuximab vedotin)Orphan drugstandardSeagen Inc.
CD30-directed Immunoconjugate [EPC]
12.1 Mechanism of Action CD30 is a member of the tumor necrosis factor receptor family and is expressed on the surface of sALCL cells and on Hodgkin R...
Shivaani Kummar, MD
NCI - Medical Oncology Branch
📍 PORTLAND, OR
Rakhee Vaidya, PA-C
Wake Forest University Health Sciences
📍 NEW YORK, NY
Alex A. Adjei, MD, PhD, MD PhD
Roswell Park Cancer Institute
📍 ROCHESTER, MN
Yago L Nieto, M.D
M.D. Anderson Cancer Center
📍 HOUSTON, TX
Oliver Abinader
Thomas Jefferson University
Jenna Mandel, MD
Thomas Jefferson University
📍 WYNNEWOOD, PA