Chronic myelomonocytic leukemia

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At a Glance

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Regulatory Watchboard

10 events
Mar 2026Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — EARLY_PHASE1

TrialRECRUITING
Jan 2026A Study of BLEX 404 Oral Liquid in Patients With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-Risk Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML)

BioLite, Inc. — PHASE2

TrialNOT YET RECRUITING
Aug 2025The Kinetics Profiling of Immune Reconstitution and Clinical Outcomes

Peking University People's Hospital

TrialNOT YET RECRUITING
Apr 2025Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

City of Hope Medical Center — PHASE2

TrialRECRUITING
Jan 2025A Phase 2 Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative Neoplasm

M.D. Anderson Cancer Center — PHASE2

TrialRECRUITING
Jan 2025Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

City of Hope Medical Center — PHASE1

TrialRECRUITING
Nov 2024IMM01+Azacitidine VS Placebo +Azacitidine in Patients With Newly Diagnosed Chronic Myelomonocytic Leukemia (CMML1-2)

ImmuneOnco Biopharmaceuticals (Shanghai) Inc. — PHASE3

TrialRECRUITING
Apr 2024Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition

Fox Chase Cancer Center — PHASE1

TrialRECRUITING
Dec 2023A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia

Otsuka Australia Pharmaceutical Pty Ltd — PHASE3

TrialACTIVE NOT RECRUITING
Oct 2023Azacitidine Combined With Venetoclax in Patients With Higher-risk Chronic Myelomonocytic Leukemia (AVENHIR)

Groupe Francophone des Myelodysplasies — PHASE2

TrialACTIVE NOT RECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

FINANCIAL LANDSCAPE SUMMARY

0

Total programs

No financial assistance programs currently listed for Chronic myelomonocytic leukemia.
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Approved Treatments

2 FDA-approved

Azacitidine

(AZACITIDINE FOR)Orphan drugstandard

Pilnova Pharma Inc

Nucleoside Metabolic Inhibitor [EPC]

12.1 Mechanism of Action Azacitidine is a pyrimidine nucleoside analog of cytidine. Azacitidine is believed to exert its antineoplastic effects by cau...

FDA label ↗

Azacitidine

(AZACITIDINE)Orphan drugstandard

Dr. Reddy's Laboratories Inc.

Nucleoside Metabolic Inhibitor [EPC]

12.1 Mechanism of Action Azacitidine for injection is a pyrimidine nucleoside analog of cytidine. Azacitidine for injection is believed to exert its a...

FDA label ↗

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Clinical Trial Landscape

25 active trials
4Phase 3
9Phase 2
5Phase 1
6PHASE1, PHASE2
1EARLY_PHASE1
25Total recruiting
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Recent News & Research

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Specialist Network

Top 6 by expertise

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