B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)

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At a Glance

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Regulatory Watchboard

3 events
May 2026Asciminib as Maintenance Treatment After Cellular Therapies for Adults With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

City of Hope Medical Center — PHASE1

TrialNOT YET RECRUITING
Apr 2026Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

University of Washington — PHASE2

TrialRECRUITING
Jan 2021Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

National Cancer Institute (NCI) — PHASE3

TrialACTIVE NOT RECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

3 programs

FINANCIAL LANDSCAPE SUMMARY

3

Total programs

3

Open now

Patient Assistance Programs3

Phyrago

Handa Therapeutics, LLC

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Scemblix

Novartis Pharmaceuticals Corporation

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Imatinib Mesylate

Mylan Institutional Inc

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Approved Treatments

5 FDA-approved

Imatinib Mesylate

(IMATINIB MESYLATE)Orphan drugstandard

Apotex Corp

12.1 Mechanism of Action Imatinib mesylate is a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase, the constitutive abnormal...

FDA label ↗

Scemblix

(asciminib)Orphan drugaccelerated

Novartis Pharmaceuticals Corporation

12.1 Mechanism of Action Asciminib is an ABL/BCR-ABL1 tyrosine kinase inhibitor. Asciminib inhibits the ABL1 kinase activity of the BCR::ABL1 fusion p...

FDA label ↗

Phyrago

(dasatinib)Orphan drugstandard

Handa Therapeutics, LLC

12.1 Mechanism of Action Dasatinib, at nanomolar concentrations, inhibits the following kinases: BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA...

FDA label ↗

Imatinib Mesylate

(IMATINIB)Orphan drugstandard

Mylan Institutional Inc

12.1 Mechanism of Action Imatinib mesylate is a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase, the constitutive abnormal...

FDA label ↗

Imkeldi

(IMATINIB ORAL)Orphan drugstandard

Shorla Oncology Inc.,

12.1 Mechanism of Action Imatinib mesylate is a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase, the constitutive abnormal...

FDA label ↗

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Clinical Trial Landscape

1 active trial
1Phase 2
1Total recruiting
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Recent News & Research

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Specialist Network

Top 6 by expertise

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