Autosomal dominant polycystic kidney disease

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At a Glance

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Regulatory Watchboard

10 events
May 2026Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease

Loma Linda University — NA

TrialNOT YET RECRUITING
Mar 2026A Study to Investigate the Effects of JMKX003142 on QTc Interval in Healthy Adults

Jemincare — PHASE1

TrialNOT YET RECRUITING
Mar 2026Mass Balance and Absolute Bioavailability Study of JMKX003142 In Healthy Volunteers

Jemincare — PHASE1

TrialNOT YET RECRUITING
Feb 2026Metabolic Impacts of Ren-Nu: A Dietary Program for Polycystic Kidney Disease

Richard Fatica — NA

TrialRECRUITING
Feb 2026Bempedoic Acid Therapy for Polycystic Kidney Disease

Kenneth Hallows — PHASE2

TrialNOT YET RECRUITING
Nov 2025Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)

Vertex Pharmaceuticals Incorporated — PHASE2

TrialRECRUITING
Nov 2025Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease

AstraZeneca — PHASE1

TrialRECRUITING
Oct 2025Drug-Drug Interaction of JMKX003142 With Amiodarone and Febuxostat in Healthy Subjects

Jemincare — PHASE1

TrialNOT YET RECRUITING
Sep 2025Somatosensory Phenotyping of ADPKD

Universitaire Ziekenhuizen KU Leuven

TrialRECRUITING
Aug 2025Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease

King's College London

TrialRECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

2 programs

FINANCIAL LANDSCAPE SUMMARY

2

Total programs

2

Open now

2

Copay cards

Copay Assistance2

Jynarque

Otsuka Pharmaceutical Company, Ltd.

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Tolvaptan

Otsuka

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Approved Treatments

1 FDA-approved

Jynarque

(tolvaptan)Orphan drug

Otsuka Pharmaceutical Company, Ltd.

Vasopressin V2 Receptor Antagonist [EPC]

12.1 Mechanism of Action Tolvaptan is a selective vasopressin V 2 -receptor antagonist with an affinity for the V 2 -receptor that is 1.8 times that o...

Approved Apr 2018FDA label ↗

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Clinical Trial Landscape

30 active trials
2Phase 3
1Phase 4
6Phase 2
2Phase 1
3N/A
16Unknown
30Total recruiting
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Recent News & Research

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Specialist Network

Top 6 by expertise

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