Anti-neutrophil cytoplasmic antibody-associated vasculitis

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At a Glance

Live from database

2FDA treatments

42Recruiting trials

Regulatory Watchboard

10 events

Jul 2026CC-97540 in Patients With Antineutrophil Cytoplasmic Antibody-associated Vasculitis

Marcela V. Maus, M.D.,Ph.D. — PHASE1, PHASE2

TrialNOT YET RECRUITING

Jun 2026Study of NM8074 in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)

NovelMed Therapeutics — PHASE2

TrialNOT YET RECRUITING

May 2026Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients

Innopeutics Corporation — PHASE1

TrialRECRUITING

Mar 2026CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy

Unlimited Biotechnology LLC — PHASE1, PHASE2

TrialRECRUITING

Mar 2026Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

Adverum Biotechnologies, Inc. — PHASE3

TrialRECRUITING

Mar 2026PBGENE-DMD Phase 1/2a Safety and Preliminary Efficacy Study in Duchenne Muscular Dystrophy (FUNCTION-DMD)

Precision BioSciences, Inc. — PHASE1, PHASE2

TrialNOT YET RECRUITING

Mar 2026Avacopan Added to Standard-of-care Therapy in ANCA-associated Vasculitis With Severe Kidney Involvement

University Hospital, Toulouse — PHASE3

TrialNOT YET RECRUITING

Mar 2026YTS109 in Pediatric Relapsed/Refractory Autoimmune Diseases

Children's Hospital of Fudan University — PHASE1

TrialNOT YET RECRUITING

Mar 2026Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases

Institute of Hematology & Blood Diseases Hospital, China — PHASE1

TrialNOT YET RECRUITING

Feb 2026Comparison of a Strategy Based on Clinico-biological Monitoring Versus Pre-emptive Rituximab Treatment in Cases of ANCA Reappearance in Granulomatosis With Polyangiitis and Microscopic Polyangiitis.

Assistance Publique - Hôpitaux de Paris — PHASE4

TrialNOT YET RECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

FINANCIAL LANDSCAPE SUMMARY

0

Total programs

No financial assistance programs currently listed for Anti-neutrophil cytoplasmic antibody-associated vasculitis.
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Approved Treatments

2 FDA-approved

Tavneos

(avacopan)Orphan drug

ChemoCentryx, Inc.

Complement 5a Receptor Antagonist [EPC]

12.1 Mechanism of Action Avacopan is a complement 5a receptor (C5aR) antagonist that inhibits the interaction between C5aR and the anaphylatoxin C5a. ...

Approved Oct 2021FDA label ↗

Megace

(Megestrol acetate)Orphan drugstandard

Bristol-Myers Squibb Pharmaceutical Research Institute

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Clinical Trial Landscape

42 active trials

5Phase 3

4Phase 4

4Phase 2

7Phase 1

4N/A

10Unknown

3EARLY_PHASE1

5PHASE1, PHASE2

42Total recruiting

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Recent News & Research

1 article

BMC NephrolMar 28, 2026

The UK Eastern Network for Kidney Inflammatory Disease (ENKID) MDT at 24 months: advancing access to high-cost drugs, clinical trials, and complex case management in renal autoimmune diseases

Published in BMC Nephrol. Francis L et al.

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Specialist Network

Top 6 by expertise

Peter A Merkel, MD, MPH

University of Pennsylvania

📍 Tampa, Florida

Score 427 trials

Peter A. Merkel, MD, MPH, MD, MPH

University of Pennsylvania

📍 RADNOR, PA

Score 398 trials

David Jayne, MD, MD

Cambridge University Hospitals NHS Foundation Trust

📍 EDMOND, OK

Score 372 trials

David Jayne, MD

Cambridge University Hospitals NHS Foundation Trust

📍 EDMOND, OK

Score 354 trials4 pubs

Michael Walsh, MD

McMaster University

Score 341 trial

Lingli Dong, MD

Tongji Hospital

Score 342 trials1 pub

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