American trypanosomiasis

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At a Glance

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Regulatory Watchboard

10 events
Jun 2026An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health

Bayer

TrialNOT YET RECRUITING
Aug 2025Prospective Evaluation of Rapid Diagnostic Tests for Trypanosoma Cruzi Infection

Instituto Nacional de Parasitologia Dr. Mario Fatala Chaben

TrialRECRUITING
Aug 2025First-in-Human Trial of Oral AN2-502998

AN2 Therapeutics, Inc — PHASE1

TrialRECRUITING
Apr 2025A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease.

Novartis Pharmaceuticals — PHASE2

TrialRECRUITING
Sep 2024University-Based Chagas Testing in Salta Province, Argentina

Mundo Sano Foundation

TrialENROLLING BY INVITATION
May 2022Cardiac Contractility Modulation in Chagas Heart Disease

InCor Heart Institute — NA

TrialRECRUITING
Jul 2021Shorter Benznidazole Regimens Compared to the Standard Regimen for Chagas Disease

Laboratorio Elea Phoenix S.A. — PHASE3

TrialRECRUITING
Jul 2021SBRT in Chagas Disease Ventricular Tachycardia

University of Sao Paulo General Hospital — PHASE1, PHASE2

TrialACTIVE NOT RECRUITING
May 2021Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF.

University of Sao Paulo General Hospital — PHASE3

TrialRECRUITING
Aug 2020

LAMPIT: FDA approved

LAMPIT is indicated in pediatric patients (birth to less than 18 years of age and weighing at least 2.5 kg) for the treatment of Chagas disease (American Trypanosomiasis), caused by Trypanosoma cruzi

FDAcompleted

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

1 program

FINANCIAL LANDSCAPE SUMMARY

1

Total programs

1

Open now

1

Copay cards

Copay Assistance1

LAMPIT

Bayer

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Approved Treatments

1 FDA-approved

LAMPIT

(nifurtimox)Orphan drug

Bayer HealthCare Pharmaceuticals, Inc.

12.1 Mechanism of Action Nifurtimox is an antiprotozoal drug [see Microbiology ( 12.4 )] . Mechanism of Action The mechanism of action of nifurtimox i...

Approved Aug 2020FDA label ↗

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Clinical Trial Landscape

6 active trials
3Phase 3
1Phase 2
1Unknown
1PHASE1, PHASE2
6Total recruiting
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Recent News & Research

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Specialist Network

Top 6 by expertise

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