Adult hepatocellular carcinoma

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At a Glance

Live from database

Regulatory Watchboard

10 events
Apr 2026Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis

University of Wisconsin, Madison — PHASE1, PHASE2

TrialRECRUITING
Apr 2026Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors

Seattle Children's Hospital — PHASE1

TrialNOT YET RECRUITING
Apr 2026Evaluation of RBS2418 in Combination With Tremelimumab Plus Durvalumab in Participants With Advanced Unresectable Hepatocellular Carcinoma

Riboscience, LLC. — PHASE2

TrialRECRUITING
Apr 2026Safety and Efficacy of LVD + C-TACE + Tis/Len for Unresectable Right-Liver HCC

Hong Wu — NA

TrialNOT YET RECRUITING
Mar 2026A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab

AstraZeneca — PHASE1

TrialNOT YET RECRUITING
Mar 2026A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

Bristol-Myers Squibb — PHASE1, PHASE2

TrialRECRUITING
Mar 2026A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Bevacizumab in Patients With Hepatocellular Carcinoma

Asan Medical Center — PHASE2

TrialRECRUITING
Mar 2026Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC

Beijing Biotech — PHASE1, PHASE2

TrialRECRUITING
Mar 2026Tislelizumab Combined With Huaier Granule as First-line Treatment for Unresectable Hepatocellular Carcinoma

Tongji Hospital — PHASE2

TrialRECRUITING
Mar 2026A Prospective, Randomized Study of TACE Combined With Sintilimab, Bevacizumab, and Ipilimumab N01 Treating Advanced HCC

Second Affiliated Hospital, School of Medicine, Zhejiang University — PHASE2

TrialNOT YET RECRUITING

Data from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Financial Assistance

5 programs

FINANCIAL LANDSCAPE SUMMARY

5

Total programs

5

Open now

3

Copay cards

Copay Assistance3

Tecentriq and Avastin

Genentech, Inc.

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Sorafenib

Bayer

OpenContact for detailsApply ↗

IMJUDO

AstraZeneca

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Patient Assistance Programs2

IMFINZI

AstraZeneca Pharmaceuticals LP

OpenContact for detailsApply ↗

Stivarga

Bayer HealthCare Pharmaceuticals, Inc.

OpenContact for details

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Approved Treatments

6 FDA-approved

IMFINZI

(durvalumab)Orphan drug

AstraZeneca Pharmaceuticals LP

Programmed Death Ligand-1 Blocker [EPC]

12.1 Mechanism of Action Expression of programmed cell death ligand-1 (PD-L1) can be induced by inflammatory signals (e.g., IFN-gamma) and can be expr...

Approved Oct 2022FDA label ↗

Imjudo

(tremelimumab-actl)Orphan drug

AstraZeneca Pharmaceuticals LP

CTLA-4-directed Blocking Antibody [EPC]

12.1 Mechanism of Action CTLA-4 is a negative regulator of T-cell activity. Tremelimumab-actl is a monoclonal antibody that binds to CTLA-4 and blocks...

Approved Oct 2022FDA label ↗

Tecentriq and Avastin

(atezolizumab + bevacizumab)Orphan drug

Genentech, Inc.

Approved May 2020

LENVIMA

(lenvatinib)Orphan drug

Eisai Inc.

Kinase Inhibitor [EPC]

12.1 Mechanism of Action Lenvatinib is a kinase inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors V...

Approved Aug 2018FDA label ↗

Stivarga

(regorafenib)Orphan drug

Bayer HealthCare Pharmaceuticals, Inc.

12.1 Mechanism of Action Regorafenib is a small molecule inhibitor of multiple membrane-bound and intracellular kinases involved in normal cellular fu...

Approved Apr 2017FDA label ↗

Nexavar

(sorafenib)Orphan drugstandard

Bayer HealthCare Pharmaceuticals, Inc.

Kinase Inhibitor [EPC]

12.1 Mechanism of Action Sorafenib is a kinase inhibitor that decreases tumor cell proliferation in vitro. Sorafenib was shown to inhibit multiple int...

FDA label ↗

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Clinical Trial Landscape

145 active trials
8Phase 3
4Phase 4
33Phase 2
23Phase 1
19N/A
39Unknown
13PHASE1, PHASE2
3PHASE2, PHASE3
3EARLY_PHASE1
145Total recruiting
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Recent News & Research

No recent news articles indexed yet for Adult hepatocellular carcinoma.
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Specialist Network

Top 6 by expertise

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